BDBM357000 (5-Amino-1-(2-methoxyphenyl)-1H-pyrazol-4-yl)(5-chloroindolin-1-yl)methanone::US10214509, Example 61

SMILES COc1ccccc1-n1ncc(C(=O)N2CCc3cc(Cl)ccc23)c1N

InChI Key InChIKey=PZCYZBNSJLDDEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357000   

TargetSodium channel protein type 9 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM357000((5-Amino-1-(2-methoxyphenyl)-1H-pyrazol-4-yl)(5-ch...)
Affinity DataIC50: 900nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM357000((5-Amino-1-(2-methoxyphenyl)-1H-pyrazol-4-yl)(5-ch...)
Affinity DataIC50: 2.80E+4nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent