BDBM357686 7-((6- phenoxypyridin- 3- yl)methyl)- 3H- [1,2,3]triazolo [4,5-b]pyridin- 5-amine::US10214527, Example 58

SMILES Nc1cc(Cc2ccc(Oc3ccccc3)nc2)c2nn[nH]c2n1

InChI Key InChIKey=VKQJJNLWOVBVSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357686   

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM357686(US10214527, Example 58 | 7-((6- phenoxypyridin- 3-...)
Affinity DataIC50: 500nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM357686(US10214527, Example 58 | 7-((6- phenoxypyridin- 3-...)
Affinity DataIC50: 5.50E+3nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog # A12222) which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent