BDBM3577 9-[(3-Bromophenyl)amino]-1H-imidazo[4,5-f]quinazoline::Anilinopyrimidine deriv. 8a::Imidazoquinazoline deriv. 15::N-(3-bromophenyl)-3,5,10,12-tetraazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),4,7,10,12-hexaen-13-amine

SMILES Brc1cccc(Nc2ncnc3ccc4[nH]cnc4c23)c1

InChI Key InChIKey=ZCTBHAZSEIICRJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3577   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3577(9-[(3-Bromophenyl)amino]-1H-imidazo[4,5-f]quinazol...)
Affinity DataIC50: 29nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3577(9-[(3-Bromophenyl)amino]-1H-imidazo[4,5-f]quinazol...)
Affinity DataIC50: 29nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2005
Entry Details Article
PubMed