BDBM35789 pyrimidine-4-carboxamide, 59

SMILES Nc1nc(cc(n1)-c1ccccc1F)C(=O)NCc1ccccn1

InChI Key InChIKey=VYYOZWHQGQCBOI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35789   

TargetAdenosine receptor A2a(Human)
Vernalis (R&D)

LigandPNGBDBM35789(pyrimidine-4-carboxamide, 59)
Affinity DataKi:  17nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Vernalis (R&D)

LigandPNGBDBM35789(pyrimidine-4-carboxamide, 59)
Affinity DataKi:  48nM ΔG°:  -9.84kcal/molepH: 7.5 T: 2°CAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed