BDBM3586 4-[(3-Bromophenyl)amino]pyrazino[2,3-g]quinazoline::N-(3-bromophenyl)pyrazino[2,3-g]quinazolin-4-amine::Pyrazinoquinazoline deriv. 24

SMILES Brc1cccc(Nc2ncnc3cc4nccnc4cc23)c1

InChI Key InChIKey=ZZAZKOOJVIBTOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3586   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3586(N-(3-bromophenyl)pyrazino[2,3-g]quinazolin-4-amine...)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2005
Entry Details Article
PubMed