BDBM35878 5,6-bis(4-chlorophenyl)-N-cyclohexylpyrazine-2-carboxamide::5,6-bis-(4-chloro-phenyl)-pyrazine-2-carboxylicacid cyclohexylamide::5,6-diaryl-pyrazine-2-amide derivative, 6d::CHEMBL227841

SMILES Clc1ccc(cc1)-c1ncc(nc1-c1ccc(Cl)cc1)C(=O)NC1CCCCC1

InChI Key InChIKey=FDSVRRAVMKJSOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35878   

TargetCannabinoid receptor 1(Human)
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM35878(5,6-bis(4-chlorophenyl)-N-cyclohexylpyrazine-2-car...)
Affinity DataIC50: 16.6nMAssay Description:Agonist activity at human CB1 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM35878(5,6-bis(4-chlorophenyl)-N-cyclohexylpyrazine-2-car...)
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2009
Entry Details Article
PubMed