BDBM3590 4-[(3-Bromophenyl)-amino]pyrido[4,3-d]pyrimidine::CHEMBL52665::N-(3-bromophenyl)pyrido[4,3-d]pyrimidin-4-amine::Pyrido[4,3-d]pyrimidine 5a

SMILES Brc1cccc(Nc2ncnc3ccncc23)c1

InChI Key InChIKey=KXQSONXECJTULQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3590   

TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3590(CHEMBL52665 | 4-[(3-Bromophenyl)-amino]pyrido[4,3-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3590(CHEMBL52665 | 4-[(3-Bromophenyl)-amino]pyrido[4,3-...)
Affinity DataIC50: 35nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2005
Entry Details Article
PubMed