BDBM361946 N-{(1S)-1-cyclopropyl-2-[(cis)- 2,6-dimethylmorpholin-4-yl]-2- oxoethyl}-9-ethyl-8-(2- methylpyrimidin-5-yl)-9H-purin- 6-amine::US10221178, Compound 2-40

SMILES CCn1c(nc2c(N[C@@H](C3CC3)C(=O)N3C[C@H](C)O[C@H](C)C3)ncnc12)-c1cnc(C)nc1

InChI Key InChIKey=RMDOWQNUSKHSQS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361946   

LigandPNGBDBM361946(N-{(1S)-1-cyclopropyl-2-[(cis)- 2,6-dimethylmorpho...)
Affinity DataIC50: 4.10nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent