BDBM362269 US9834548, Example 64

SMILES NC(=O)c1nnc(Nc2ccc(cn2)N2CCOCC2)cc1NCc1cccc(F)c1

InChI Key InChIKey=FKLHNCDUFMRGDR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 362269   

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM362269(US9834548, Example 64)
Affinity DataIC50: 5.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM362269(US9834548, Example 64)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM362269(US9834548, Example 64)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
US Patent