BDBM362281 US9834548, Example 75

SMILES CC(C)[C@@H](C)Nc1cc(Nc2ccc(cc2)N2CCN(CC2)C(C)=O)nnc1C(N)=O

InChI Key InChIKey=FJXRAHZMMKRGET-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 362281   

TargetTyrosine-protein kinase JAK2(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM362281(US9834548, Example 75)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM362281(US9834548, Example 75)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM362281(US9834548, Example 75)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
US Patent