BDBM362348 N-(3-(3-chloro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)acrylamide ::US9834551, Example 4

SMILES OCc1ccc2cc([nH]c2c1)-c1c[nH]c2ncc(nc12)-c1cccc(NC(=O)C=C)c1

InChI Key InChIKey=ALDRDUUTGKRUGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362348   

TargetTyrosine-protein kinase ITK/TSK(Human)
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM362348(US9834551, Example 4 | N-(3-(3-chloro-1H-pyrrolo[2...)
Affinity DataIC50: 100nMAssay Description:ITK and JAK3 Kinase assay procedures:Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM362348(US9834551, Example 4 | N-(3-(3-chloro-1H-pyrrolo[2...)
Affinity DataIC50: 100nMAssay Description:ITK and JAK3 Kinase assay procedures:Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent