BDBM362712 (RS)-6-Morpholin-2-yl-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine::US9840501, Example 6

SMILES FC(F)(F)c1ccc(Nc2ccc(nc2)C2CNCCO2)cc1

InChI Key InChIKey=CWRDKDSHVOKMNB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362712   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM362712(US9840501, Example 6 | (RS)-6-Morpholin-2-yl-N-[4-...)
Affinity DataKi:  3.30nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM362712(US9840501, Example 6 | (RS)-6-Morpholin-2-yl-N-[4-...)
Affinity DataKi:  15.9nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
US Patent