BDBM362753 N-(5-Bromo-2-pyridyl)-6-[(2R)-morpholin-2-yl]pyridin-3-amine::US9840501, Example 47

SMILES Brc1ccc(Nc2ccc(nc2)[C@H]2CNCCO2)nc1

InChI Key InChIKey=PNLLNPQSZMJRQJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362753   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM362753(US9840501, Example 47 | N-(5-Bromo-2-pyridyl)-6-[(...)
Affinity DataKi:  3.90nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM362753(US9840501, Example 47 | N-(5-Bromo-2-pyridyl)-6-[(...)
Affinity DataKi:  164nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
US Patent