BDBM362788 4-Chloro-3-ethyl-N-[6-[(2R)-morpholin-2-yl]-3-pyridyl]-1H-pyrazole-5-carboxamide::US9840501, Example 82

SMILES CCc1n[nH]c(C(=O)Nc2ccc(nc2)[C@H]2CNCCO2)c1Cl

InChI Key InChIKey=XTNGAVWZAVURFP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362788   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM362788(US9840501, Example 82 | 4-Chloro-3-ethyl-N-[6-[(2R...)
Affinity DataKi:  3.90nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM362788(US9840501, Example 82 | 4-Chloro-3-ethyl-N-[6-[(2R...)
Affinity DataKi:  92.5nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
US Patent