BDBM362879 2-((trans-4-ethoxycyclohexyl)methyl)-N-((S)-1-(4-(ethylsulfonyl)phenyl)-3-hydroxypropyl)-1-isopropylisoindoline-5-carboxamide (10a) and (10b)::US9845308, Example 10a

SMILES CCO[C@H]1CC[C@H](CN2Cc3cc(ccc3[C@@H]2C(C)C)C(=O)N[C@@H](CCO)c2ccc(cc2)S(=O)(=O)CC)CC1

InChI Key InChIKey=LWCOOEOLODHYQJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 362879   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM362879(US9845308, Example 10a | 2-((trans-4-ethoxycyclohe...)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
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Date in BDB:
11/14/2019
Entry Details
US Patent