BDBM362894 (S)-1-isopropyl-2-((4-methoxy-4-(trifluoromethyl)cyclohexyl)methyl)-N-((1-(methylsulfonyl)piperidin-4-yl)methyl)isoindoline-5-carboxamide Isomers::US9845308, Example 14b

SMILES COC1(CCC(CN2Cc3cc(ccc3[C@H]2C(C)C)C(=O)NCC2CCN(CC2)S(C)(=O)=O)CC1)C(F)(F)F

InChI Key InChIKey=MRJIONSESBTBRV-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 362894   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM362894(US9845308, Example 14b | (S)-1-isopropyl-2-((4-met...)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent