BDBM363082 (S)-2-((2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1′-biphenyl]-3-yl)methoxy)benzyl)amino)-3-hydroxypropanoic acid::US9850225, Example 1018

SMILES Cc1c(COc2ccc(CN[C@@H](CO)C(O)=O)c(OCc3cccc(c3)C#N)c2)cccc1-c1ccccc1

InChI Key InChIKey=OUEOAVHGVDLFGR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 363082   

TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM363082(US9850225, Example 1018 | (S)-2-((2-((3-cyanobenzy...)
Affinity DataIC50: 5.30nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM363082(US9850225, Example 1018 | (S)-2-((2-((3-cyanobenzy...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as disruption of PD-1/PD-L1 complex incubated for 2 hrs by Tag-1 Eu3+ and anti-Tag2-XL665 based H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed