BDBM36326 US8546380, 176::US8633188, 176

SMILES COCc1cc(NC(=O)c2ccco2)cc(c1)C1(C)CCSC(N)=N1

InChI Key InChIKey=JTRGZWVQZWTHDK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 36326   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM36326(US8633188, 176 | US8546380, 176)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM36326(US8633188, 176 | US8546380, 176)
Affinity DataIC50: 1.48E+3nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
Go to US Patent