BDBM363369 (S)-2-(2-((5-cyanopyridin-3-yl)methoxy)-4-(3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyloxy)-5-methylbenzylamino)-3-hydroxypropanoic acid::US9850225, Example 1284

SMILES Cc1cc(CN[C@@H](CO)C(O)=O)c(OCc2cncc(c2)C#N)cc1OCc1cccc(c1C)-c1ccc2OCCOc2c1

InChI Key InChIKey=YRACWCUSAGLZCG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 363369   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM363369((S)-2-(2-((5-cyanopyridin-3-yl)methoxy)-4-(3-(2,3-...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of PD-1/PD-L1 interaction (unknown origin) by HTRF binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM363369((S)-2-(2-((5-cyanopyridin-3-yl)methoxy)-4-(3-(2,3-...)
Affinity DataIC50: 5.30nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent