BDBM36343 CID24762173::N2-trans-(4-Amino-cyclohexyl)-N6-(4-morpholin-4-ylmethyl-phenyl)-9-phenyl-9H-purine-2,6-diamine, 11

SMILES N[C@H]1CC[C@H](Nc2nc(Nc3ccc(CN4CCOCC4)cc3)c3ncn(-c4ccccc4)c3n2)CC1

InChI Key InChIKey=WXTHNIOSZSQDJR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 36343   

TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
The Scripps Research Institute

LigandChemical structure of BindingDB Monomer ID 36343BDBM36343(CID24762173 | N2-trans-(4-Amino-cyclohexyl)-N6-(4-...)
Affinity DataEC50:  174nMpH: 7.5 T: 2°CAssay Description:This parasite proliferation assay, a modification of published DNA intercalating fluorescent dye-based assay, was adapted to 384-well plate format an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
The Scripps Research Institute

LigandChemical structure of BindingDB Monomer ID 36343BDBM36343(CID24762173 | N2-trans-(4-Amino-cyclohexyl)-N6-(4-...)
Affinity DataIC50: 703nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed