BDBM364487 2-fluoro-N-[5-(2-hydroxyethyl)-2- phenyl-2H-indazol-3-yl]-5- pyrimidin-2-yl-4- (trifluoromethyl)benzamide::US9862707, Example 61

SMILES OCCc1ccc2nn(c(NC(=O)c3cc(-c4ncccn4)c(cc3F)C(F)(F)F)c2c1)-c1ccccc1

InChI Key InChIKey=PVWWJVBOYHULJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364487   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM364487(US9862707, Example 61 | 2-fluoro-N-[5-(2-hydroxyet...)
Affinity DataIC50: 3.10nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent