BDBM364503 3-({[2-fluoro-5-(1H-pyrazol-3-yl)- 4- (trifluoromethyl)phenyl]carbonyl} amino)-2-phenyl-2H-indazole-6- carboxamide::US9862707, Example 78

SMILES NC(=O)c1ccc2c(NC(=O)c3cc(-c4cc[nH]n4)c(cc3F)C(F)(F)F)n(nc2c1)-c1ccccc1

InChI Key InChIKey=VVZWYJXHLGUKAL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364503   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM364503(US9862707, Example 78 | 3-({[2-fluoro-5-(1H-pyrazo...)
Affinity DataIC50: 3.60nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent