BDBM36552 Prochelators, 2

SMILES CN(CC#C)Cc1ccc(OC(=O)N(C)C)c2ncccc12

InChI Key InChIKey=JWUFDSSCTMPGLI-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 36552   

TargetAcetylcholinesterase(Rat)
The Weizmann Institute of Science

LigandPNGBDBM36552(Prochelators, 2)
Affinity DataIC50: 520nMpH: 7.4 T: 2°CAssay Description:Inhibition of AChE and BChE activity in rat brain homogenates using Ellman's method. More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
The Weizmann Institute of Science

LigandPNGBDBM36552(Prochelators, 2)
Affinity DataIC50: 4.49E+4nMpH: 7.4 T: 2°CAssay Description:Inhibition of AChE and BChE activity in rat brain homogenates using Ellman's method. More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
The Weizmann Institute of Science

LigandPNGBDBM36552(Prochelators, 2)
Affinity DataIC50: 7.70nMpH: 7.4 T: 2°CAssay Description:Inhibition of MAO activity in rat brain homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
The Weizmann Institute of Science

LigandPNGBDBM36552(Prochelators, 2)
Affinity DataIC50: 7.90E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of MAO activity in rat brain homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
The Weizmann Institute of Science

LigandPNGBDBM36552(Prochelators, 2)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of rat MAO-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
The Weizmann Institute of Science

LigandPNGBDBM36552(Prochelators, 2)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of rat MAO-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Laboratorio De Quimica Medica (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM36552(Prochelators, 2)
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells preincubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
Laboratorio De Quimica Medica (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM36552(Prochelators, 2)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of recombinant human BuChE expressed in HEK293 cells preincubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed