BDBM367271 US10226464, Compound 38

SMILES CC(C)COc1cc2oc3nc(=O)[nH]c(=O)c3cc2cc1Cl

InChI Key InChIKey=ADBDKMJPIOTSDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367271   

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Immunetarget

US Patent
LigandPNGBDBM367271(US10226464, Compound 38)
Affinity DataIC50: 500nMAssay Description:DNA binding reaction (20 μL) was carried out in 1×DNA Binding Buffer (10 mM Tris, 40 mM NaCl, 1 mM EDTA, 4% glycerol) with 10 nM c-Rel protein a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Immunetarget

US Patent
LigandPNGBDBM367271(US10226464, Compound 38)
Affinity DataIC50: 2.00E+4nMAssay Description:NFκB/Jurkat/GFP transcriptional reporter cell line was obtained from SBI System Biosciences. NF-κB/Jurkat/GFP Reporter cells (5×105 cells) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent