BDBM367277 US10226464, Compound 44

SMILES CCCCCCOc1ccc2cc3c(nc(=O)[nH]c3=O)oc2c1Cl

InChI Key InChIKey=QMZWIPOPYWLWCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367277   

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Immunetarget

US Patent
LigandPNGBDBM367277(US10226464, Compound 44)
Affinity DataIC50: 500nMAssay Description:DNA binding reaction (20 μL) was carried out in 1×DNA Binding Buffer (10 mM Tris, 40 mM NaCl, 1 mM EDTA, 4% glycerol) with 10 nM c-Rel protein a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Immunetarget

US Patent
LigandPNGBDBM367277(US10226464, Compound 44)
Affinity DataIC50: 3.00E+3nMAssay Description:NFκB/Jurkat/GFP transcriptional reporter cell line was obtained from SBI System Biosciences. NF-κB/Jurkat/GFP Reporter cells (5×105 cells) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent