BDBM368194 US10227332, No. 8

SMILES CCCCCn1c2ccccc2c2cc(ccc12)C(=O)N1CCNCC1

InChI Key InChIKey=FPWGARRGHTWQJZ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 368194   

TargetCannabinoid receptor 1(Rat)
Uti Limited Partnership

US Patent
LigandPNGBDBM368194(US10227332, No. 8)
Affinity DataKi:  283nMAssay Description:The structure-activity relationship and optimization studies have led to the discovery of selective T-type calcium channel blockers, e.g., compound 9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Rat)
Uti Limited Partnership

US Patent
LigandPNGBDBM368194(US10227332, No. 8)
Affinity DataKi:  283nMAssay Description:Displacement of [3H]-CP55940 from CB1 receptor in rat brain homogenate after 1.5 hrs by microbeta liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Uti Limited Partnership

US Patent
LigandPNGBDBM368194(US10227332, No. 8)
Affinity DataKi:  2.83E+3nMAssay Description:The structure-activity relationship and optimization studies have led to the discovery of selective T-type calcium channel blockers, e.g., compound 9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Uti Limited Partnership

US Patent
LigandPNGBDBM368194(US10227332, No. 8)
Affinity DataKi:  2.83E+3nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cells after 1.5 hrs by microbeta liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed