BDBM368498 1-(fluoromethyl)-N-(1H- pyrazolo[4,3-b]pyridin- 3-yl)isoquinolin-6- amine::US10227343, Example 31

SMILES FCc1nccc2cc(Nc3n[nH]c4cccnc34)ccc12

InChI Key InChIKey=YHTOVHCLFZXACM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368498   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM368498(1-(fluoromethyl)-N-(1H- pyrazolo[4,3-b]pyridin- 3-...)
Affinity DataEC50:  44nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent