BDBM368502 4-fluoro-1-(5-fluoro-3- pyridyl)-N-(1H-pyrazolo [4,3-b]pyridin-3-yl) isoquinolin-6-amine::US10227343, Example 35

SMILES Fc1cncc(c1)-c1ncc(F)c2cc(Nc3n[nH]c4cccnc34)ccc12

InChI Key InChIKey=MDLKQEVUYXVECT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368502   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM368502(4-fluoro-1-(5-fluoro-3- pyridyl)-N-(1H-pyrazolo [4...)
Affinity DataEC50:  105nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent