BDBM368559 N1-methyl-N6-(1H- pyrazolo [4,3-b]pyridin-3-yl)-N1- (2,2,2-trifluoroethyl) isoquinoline- 1,6-diamine::US10227343, Example 147

SMILES CN(CC(F)(F)F)c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12

InChI Key InChIKey=AVFUCIJEQZJYAG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368559   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM368559(N1-methyl-N6-(1H- pyrazolo [4,3-b]pyridin-3-yl)-N1...)
Affinity DataEC50:  56.1nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent