BDBM368562 (4,4-difluoro-1-piperidyl)- [6-(1H-pyrazolo[3,4-b] pyrazin-3-ylamino)-1- naphthyl]methanone::US10227343, Example 163

SMILES FC1(F)CCN(CC1)C(=O)c1cccc2cc(Nc3n[nH]c4nccnc34)ccc12

InChI Key InChIKey=UTZAZQLIUMLROX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368562   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM368562((4,4-difluoro-1-piperidyl)- [6-(1H-pyrazolo[3,4-b]...)
Affinity DataEC50:  154nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent