BDBM368572 1-(1,1-difluorobutyl)-N- (1H- pyrazolo[4,3-b]pyridin-3- yl)isoquinolin-6-amine::US10227343, Example 173

SMILES CCCC(F)(F)c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12

InChI Key InChIKey=MNXDUKLWDBITEX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368572   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM368572(1-(1,1-difluorobutyl)-N- (1H- pyrazolo[4,3-b]pyrid...)
Affinity DataEC50:  34.4nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent