BDBM368579 N-(6-fluoro-1H-pyrazolo [4,3-b]pyridin-3-yl)-1- (trifluoromethyl) isoquinolin-6-amine::US10227343, Example 182

SMILES Fc1cnc2c(Nc3ccc4c(nccc4c3)C(F)(F)F)n[nH]c2c1

InChI Key InChIKey=CLPJIADXUWFGAE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368579   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM368579(N-(6-fluoro-1H-pyrazolo [4,3-b]pyridin-3-yl)-1- (t...)
Affinity DataEC50:  38.5nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent