BDBM368643 US10227350, Compound 62

SMILES Nc1cc(ccn1)-c1cc(-c2nnc[nH]2)c2nc(C3CC3)n(-c3ccnc4c(Cl)ccc(F)c34)c2c1

InChI Key InChIKey=NNRYPUZSTUSSQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368643   

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandPNGBDBM368643(US10227350, Compound 62)
Affinity DataIC50: 8nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent