BDBM36888 4-(3,4-dihydro-1H-isoquinolin-2-yl)-5H-pyrimid[5,4-b]indole::4-(3,4-dihydro-1H-isoquinolin-2-yl)-5H-pyrimido[5,4-b]indole::MLS000078381::SMR000039631::cid_658734

SMILES C1Cc2ccccc2CN1c1ncnc2c3ccccc3[nH]c12

InChI Key InChIKey=LSBGYWOQKNFBPD-UHFFFAOYSA-N

Data  6 IC50  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 36888   

TargetATP-dependent molecular chaperone HSP82(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM36888(SMR000039631 | MLS000078381 | cid_658734 | 4-(3,4-...)
Affinity DataEC50:  558nMAssay Description:Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36888(SMR000039631 | MLS000078381 | cid_658734 | 4-(3,4-...)
Affinity DataEC50:  1.18E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2011
Entry Details
PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36888(SMR000039631 | MLS000078381 | cid_658734 | 4-(3,4-...)
Affinity DataEC50:  1.19E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36888(SMR000039631 | MLS000078381 | cid_658734 | 4-(3,4-...)
Affinity DataIC50: 1.41E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36888(SMR000039631 | MLS000078381 | cid_658734 | 4-(3,4-...)
Affinity DataIC50: 2.99E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36888(SMR000039631 | MLS000078381 | cid_658734 | 4-(3,4-...)
Affinity DataIC50: 3.34E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetCOUP transcription factor 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36888(SMR000039631 | MLS000078381 | cid_658734 | 4-(3,4-...)
Affinity DataIC50: 4.69E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2013
Entry Details
PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36888(SMR000039631 | MLS000078381 | cid_658734 | 4-(3,4-...)
Affinity DataEC50:  5.88E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2011
Entry Details
PCBioAssay
TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36888(SMR000039631 | MLS000078381 | cid_658734 | 4-(3,4-...)
Affinity DataIC50: 9.03E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetTegument protein VP16(HHV-1)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36888(SMR000039631 | MLS000078381 | cid_658734 | 4-(3,4-...)
Affinity DataIC50: 5.38E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM36888(SMR000039631 | MLS000078381 | cid_658734 | 4-(3,4-...)
Affinity DataEC50: >1.50E+5nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, stress response Primary Collaborators: Susan Lindquist, Whitehead Insti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM36888(SMR000039631 | MLS000078381 | cid_658734 | 4-(3,4-...)
Affinity DataEC50: >1.50E+5nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, stress response Assay Overview: Method for determining if compound acts as Hsp90 inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetSerine/threonine-protein phosphatase(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM36888(SMR000039631 | MLS000078381 | cid_658734 | 4-(3,4-...)
Affinity DataEC50:  1.80E+5nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay