BDBM369030 N-[4-(6-methyl-7H-pyrrolo[2,3- d]pyrimidin-4-yl)phenyl]-1,3- benzodioxole-5-sulfonamide::US10227357, Compound P-0294

SMILES Cc1cc2c(ncnc2[nH]1)-c1ccc(NS(=O)(=O)c2ccc3OCOc3c2)cc1

InChI Key InChIKey=OSOXVTLOOXQSEI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 369030   

LigandPNGBDBM369030(US10227357, Compound P-0294 | N-[4-(6-methyl-7H-py...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent
LigandPNGBDBM369030(US10227357, Compound P-0294 | N-[4-(6-methyl-7H-py...)
Affinity DataKi:  1.05E+5nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent