BDBM369031 4-fluoro-N-[4-[6-(2,2,6,6-tetramethyl- 1,3-dihydropyridin-4-yl)-7H-pyrrolo[2,3- d]pyrimidin-4- yl]phenyl]benzenesulfonamide::US10227357, Compound P-0295

SMILES CC1(C)CC(=CC(C)(C)N1)c1cc2c(ncnc2[nH]1)-c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1

InChI Key InChIKey=XZUFMKVARKYYFF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 369031   

LigandPNGBDBM369031(US10227357, Compound P-0295 | 4-fluoro-N-[4-[6-(2,...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent
LigandPNGBDBM369031(US10227357, Compound P-0295 | 4-fluoro-N-[4-[6-(2,...)
Affinity DataKi:  5.50E+3nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent