BDBM369076 4-[6-(2,4-difluorophenyl)-7H-pyrrolo[2,3- d]pyrimidin-4-yl]-3-fluoro-aniline::US10227357, Compound P-0341

SMILES Nc1ccc(c(F)c1)-c1ncnc2[nH]c(cc12)-c1ccc(F)cc1F

InChI Key InChIKey=ZDFKHXLNNULNPO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369076   

LigandPNGBDBM369076(US10227357, Compound P-0341 | 4-[6-(2,4-difluoroph...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent