BDBM369083 2-fluoro-N-[2-fluoro-4-(6-methyl-7H- pyrrolo[2,3-d]pyrimidin-4- yl)phenyl]benzenesulfonamide::US10227357, Compound P-0348

SMILES Cc1cc2c(ncnc2[nH]1)-c1ccc(NS(=O)(=O)c2ccccc2F)c(F)c1

InChI Key InChIKey=MRDZHRREWYWGCH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369083   

TargetMast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent
LigandPNGBDBM369083(US10227357, Compound P-0348 | 2-fluoro-N-[2-fluoro...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent