BDBM369087 4-chloro-2-fluoro-N-[3-fluoro-4-(6- methyl-7H-pyrrolo[2,3-d]pyrimidin-4- yl)phenyl]benzenesulfonamide::US10227357, Compound P-0352

SMILES Cc1cc2c(ncnc2[nH]1)-c1ccc(NS(=O)(=O)c2ccc(Cl)cc2F)cc1F

InChI Key InChIKey=SWYKCBANJJEZOQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 369087   

TargetMast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent
LigandPNGBDBM369087(US10227357, Compound P-0352 | 4-chloro-2-fluoro-N-...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

LigandPNGBDBM369087(US10227357, Compound P-0352 | 4-chloro-2-fluoro-N-...)
Affinity DataKi:  5.50E+3nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent