BDBM371284 7-Fluoro-N-(1-methylcyclopropyl)-1-[(3-methylisoxazol-5-yl)methyl]-3-[(1-methylpyrazol-4-yl)methyl]-2,4-dioxo-quinazoline-6-sulfonamide::US10239843, Example 391

SMILES Cc1cc(Cn2c3cc(F)c(cc3c(=O)n(Cc3cnn(C)c3)c2=O)S(=O)(=O)NC2(C)CC2)on1

InChI Key InChIKey=SHLFQNZZZIKXMJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371284   

TargetPoly(ADP-ribose) glycohydrolase(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM371284(US10239843, Example 391 | 7-Fluoro-N-(1-methylcycl...)
Affinity DataIC50: 24nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
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Date in BDB:
12/30/2019
Entry Details
US Patent