BDBM371481 N-[1-(Fluoromethyl)cyclopropyl]-3-[(1-methylpyrazol-4-yl)methyl]-2,4-dioxo-1-(1H-pyrazol-4-ylmethyl)quinazoline-6-sulfonamide::US10239843, Example 590

SMILES Cn1cc(Cn2c(=O)n(CC3C=NN=C3)c3ccc(cc3c2=O)S(=O)(=O)NC2(CF)CC2)cn1

InChI Key InChIKey=BUXTXRWZCSPZAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371481   

TargetPoly(ADP-ribose) glycohydrolase(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM371481(US10239843, Example 590 | N-[1-(Fluoromethyl)cyclo...)
Affinity DataIC50: 30nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
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Date in BDB:
12/30/2019
Entry Details
US Patent