BDBM371521 4-chloro-2-methyl-5-((1-methylazepan-3-yl)amino)pyridazin-3(2H)-one::US10239861, Example 1::US10239861, Example 12

SMILES CN1CCCCC(C1)Nc1cnn(C)c(=O)c1Cl

InChI Key InChIKey=FFWRQIIGTISRFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371521   

TargetHistone acetyltransferase KAT2B(Human)
Genetech

US Patent
LigandPNGBDBM371521(4-chloro-2-methyl-5-((1-methylazepan-3-yl)amino)py...)
Affinity DataIC50: 62nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetHistone acetyltransferase KAT2B(Human)
Genetech

US Patent
LigandPNGBDBM371521(4-chloro-2-methyl-5-((1-methylazepan-3-yl)amino)py...)
Affinity DataIC50: 165nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent