BDBM371537 (E)-2-(but-2-en-1-yl)-4-chloro-5-((1-methylazepan-3-yl)amino)pyridazin-::US10239861, Example 17

SMILES C\C=C\CN1NC=C(NC2CCCCN(C)C2)C(Cl)=C1

InChI Key InChIKey=SOLXTQKCZRTDMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371537   

TargetHistone acetyltransferase KAT2B(Human)
Genetech

US Patent
LigandPNGBDBM371537((E)-2-(but-2-en-1-yl)-4-chloro-5-((1-methylazepan-...)
Affinity DataIC50: 312nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent