BDBM371544 4-chloro-2-methyl-5-((1-methyl-5-phenylpiperidin-3-yl)amino)pyridazin-3(2H)-one::US10239861, Example 24

SMILES CN1CC(CC(C1)c1ccccc1)Nc1cnn(C)c(=O)c1Cl

InChI Key InChIKey=ZJYJXUJUQQPMJB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371544   

TargetHistone acetyltransferase KAT2B(Human)
Genetech

US Patent
LigandPNGBDBM371544(4-chloro-2-methyl-5-((1-methyl-5-phenylpiperidin-3...)
Affinity DataIC50: 167nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent