BDBM371564 4-chloro-5-[[1-[[3-(difluoromethoxy)phenyl]methyl]-3-piperidyl]amino]-2-methyl-pyridazin-3-one::US10239861, Example 44

SMILES Cn1ncc(NC2CCCN(Cc3cccc(OC(F)F)c3)C2)c(Cl)c1=O

InChI Key InChIKey=UQCACBFVZZOFTO-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371564   

TargetHistone acetyltransferase KAT2B(Human)
Genetech

US Patent
LigandPNGBDBM371564(4-chloro-5-[[1-[[3-(difluoromethoxy)phenyl]methyl]...)
Affinity DataIC50: 94.9nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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