BDBM371573 4-chloro-2-methyl-5-[[1-[(5-methyl-3-pyridyl)methyl]-3-piperidyl]amino]pyridazin-3-one::US10239861, Example 53

SMILES Cc1cncc(CN2CCCC(C2)Nc2cnn(C)c(=O)c2Cl)c1

InChI Key InChIKey=MKFXKMFXWYVNHE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371573   

TargetHistone acetyltransferase KAT2B(Human)
Genetech

US Patent
LigandPNGBDBM371573(4-chloro-2-methyl-5-[[1-[(5-methyl-3-pyridyl)methy...)
Affinity DataIC50: 441nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent