BDBM371576 4-chloro-5-[[1-[(4-fluorophenyl)methyl]-3-piperidyl]amino]-2-methyl-pyridazin-3-one::US10239861, Example 56

SMILES Cn1ncc(NC2CCCN(Cc3ccc(F)cc3)C2)c(Cl)c1=O

InChI Key InChIKey=HAJDMVOUJGHBCO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371576   

TargetHistone acetyltransferase KAT2B(Human)
Genetech

US Patent
LigandPNGBDBM371576(4-chloro-5-[[1-[(4-fluorophenyl)methyl]-3-piperidy...)
Affinity DataIC50: 139nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent