BDBM372149 N-(4-((1- methylpiperidin-4- yl)oxy)phenyl)-6- (o-tolyl)-5H- pyrrolo[3,2-d] pyrimidin-2-amine::US10239881, Example A2::US10875863, Example A2

SMILES CN1CCC(CC1)Oc1ccc(Nc2ncc3[nH]c(cc3n2)-c2ccccc2C)cc1

InChI Key InChIKey=AMDFLHAIQPFUKC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372149   

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University Health Network

US Patent
LigandPNGBDBM372149(US10239881, Example A2 | N-(4-((1- methylpiperidin...)
Affinity DataIC50: 100nMAssay Description:RIPK2 activity was measured using an indirect ELISA detection system. His RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University Health Network

US Patent
LigandPNGBDBM372149(US10239881, Example A2 | N-(4-((1- methylpiperidin...)
Affinity DataIC50: 100nMAssay Description:Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent