BDBM372156 N-(3-((4- methylpiperazin-1- yl)methyl)phenyl)- 6-(o-tolyl)-5H- pyrrolo[3,2-d] pyrimidin-2-amine::US10239881, Example A9::US10875863, Example A9

SMILES CN1CCN(Cc2cccc(Nc3ncc4[nH]c(cc4n3)-c3ccccc3C)c2)CC1

InChI Key InChIKey=SPVDVGUFWOPGCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372156   

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University Health Network

US Patent
LigandPNGBDBM372156(US10239881, Example A9 | N-(3-((4- methylpiperazin...)
Affinity DataIC50: 100nMAssay Description:RIPK2 activity was measured using an indirect ELISA detection system. His RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University Health Network

US Patent
LigandPNGBDBM372156(US10239881, Example A9 | N-(3-((4- methylpiperazin...)
Affinity DataIC50: 100nMAssay Description:Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent