BDBM372173 N-((1- morpholino- cyclopentyl) methyl)-6- (o-tolyl)- 5H-pyrrolo[3,2- d]pyrimidin-2- amine::US10239881, Example A26::US10875863, Example A26

SMILES Cc1ccccc1-c1cc2nc(NCC3(CCCC3)N3CCOCC3)ncc2[nH]1

InChI Key InChIKey=UZVKIIMONNWMJQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372173   

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University Health Network

US Patent
LigandPNGBDBM372173(US10239881, Example A26 | N-((1- morpholino- cyclo...)
Affinity DataIC50: 500nMAssay Description:RIPK2 activity was measured using an indirect ELISA detection system. His RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University Health Network

US Patent
LigandPNGBDBM372173(US10239881, Example A26 | N-((1- morpholino- cyclo...)
Affinity DataIC50: 500nMAssay Description:Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent